PLCG

A phosphoinositide phospholipase C subtype that is primarily regulated by PROTEIN-TYROSINE KINASES. It is structurally related to PHOSPHOLIPASE C DELTA with the addition of SRC HOMOLOGY DOMAINS and pleckstrin homology domains located between two halves of the CATALYTIC DOMAIN. (mesh:D051966)

Cross-references

• MESH:D051966 - Phospholipase C gamma
• RE:R-HSA-2029095
• SFAM:F0180
• IP:IPR016279
• RE:R-HSA-1168365
• NCIT:C126114
• RE:R-HSA-1169089
• IP:IPR035023
• RE:R-HSA-1169086
• BEL:PLCG Family
• RE:R-HSA-2685653
• IP:IPR035024

Synonyms

Synonym	Reference	Specificity
PLC-γ		Exact
PLC-gamma		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:9065	PLCG1	isa
HGNC:9066	PLCG2	isa

Outgoing Relations

Relation	Identifier	Name
isa	FPLX:PLC	PLC