A multisubunit polycomb protein complex with affinity for CHROMATIN that contains methylated HISTONE H3. It contains an E3 ubiquitin ligase activity that is specific for HISTONE H2A and works in conjunction with POLYCOMB REPRESSIVE COMPLEX 2 to effect EPIGENETIC REPRESSION. (mesh:D063150)



Synonym Reference Specificity
Polycomb Repressive Complexes 1 Exact
Polycomb Repressive Complex 1 Exact
Polycomb-repressive complex 1 Exact
polycomb Repressive Complex (PRC) 1 Exact
Polycomb repressive complex 1 Exact
Polycomb repressive complex PRC1 Exact
polycomb repressive complex 1 Exact

Incoming Relations

Identifier Name Relation
HGNC:3183 PHC2 partof
HGNC:12918 ZNF134 partof
HGNC:3182 PHC1 partof
HGNC:15682 PHC3 partof
HGNC:1554 CBX4 partof
HGNC:8919 PHF1 partof
HGNC:19003 SCMH1 partof
HGNC:1552 CBX2 partof
HGNC:10018 RING1 partof
HGNC:10061 RNF2 partof
HGNC:12856 YY1 partof
HGNC:15962 CBX8 partof
HGNC:1066 BMI1 partof
HGNC:12929 PCGF2 partof

Outgoing Relations

None available.