PYG

An enzyme that catalyzes the degradation of GLYCOGEN in animals by releasing glucose-1-phosphate from the terminal alpha-1,4-glycosidic bond. This enzyme exists in two forms: an active phosphorylated form ( PHOSPHORYLASE A) and an inactive un-phosphorylated form (PHOSPHORYLASE B). Both a and b forms of phosphorylase exist as homodimers. In mammals, the major isozymes of glycogen phosphorylase are found in muscle, liver and brain tissue. (mesh:D024981)

Cross-references

• MESH:D024981 - Glycogen Phosphorylase
• SIGNOR:SIGNOR-PF96

Synonyms

Synonym	Reference	Specificity
Glycogen phosphorylase		Exact
glycogen phosphorylases		Exact
PYG		Exact
Glycogen phosphorylases		Exact
glycogen phosphorylase		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:9726	PYGM	isa
HGNC:9723	PYGB	isa
HGNC:9725	PYGL	isa

Outgoing Relations

Relation	Identifier	Name
isa	FPLX:Glycosyltransferase	Glycosyltransferase