Patched

A family of 12-pass transmembrane proteins originally identified in Drosophila that are receptors for HEDGEHOG PROTEINS. They have important roles in regulating CELL PROLIFERATION; CELL DIFFERENTIAION; and BODY PATTERNING and may also function as TUMOR SUPPRESSOR PROTEINS. (mesh:D000072079)

Cross-references

• RE:R-HSA-445134
• MESH:D000072079 - Patched Receptors
• PF:PF02460
• IP:IPR004766
• MEDSCAN:urn:agi-aopfc:0000281

Synonyms

Synonym	Reference	Specificity
Patched		Exact
PATCHED		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:9586	PTCH2	isa
HGNC:9585	PTCH1	isa

Outgoing Relations

None available.