A family of closely-related serine-threonine kinases that were originally identified as the cellular homologs of the retrovirus-derived V-RAF KINASES. They are MAP kinase kinase kinases that play important roles in SIGNAL TRANSDUCTION. (mesh:D048490)
Synonym | Reference | Specificity |
raf protein | Exact | |
RAF | Exact | |
Raf | Exact |
Identifier | Name | Relation |
HGNC:9829 | RAF1 | isa |
HGNC:646 | ARAF | isa |
HGNC:1097 | BRAF | isa |
Relation | Identifier | Name |
isa | FPLX:MAP3K | MAP3K |