RFC

A DNA-binding protein and AAA ATPase that consists of 5 polypeptides and plays an essential role in DNA REPLICATION in eukaryotes. It binds DNA PRIMER-template junctions and recruits PROLIFERATING CELL NUCLEAR ANTIGEN and DNA POLYMERASES to the site of DNA synthesis. (mesh:D051818)

Cross-references

• RE:R-HSA-174454
• SCOMP:C0108
• BEL:RFC Complex
• MEDSCAN:urn:agi-complex:prophash-7629c2cdfdf4908b72f13917a7c1551e
• RE:R-HSA-68436
• MESH:D051818 - Replication Protein C
• GO:GO:0005663 - DNA replication factor C complex

Synonyms

Synonym	Reference	Specificity
RF-C		Exact
RFC		Exact
DNA replication factor C		Exact
replication factor C		Exact
DNA replication factor C complex		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:9972	RFC4	partof
HGNC:9973	RFC5	partof
HGNC:9971	RFC3	partof
HGNC:9970	RFC2	partof
HGNC:9969	RFC1	partof

Outgoing Relations

None available.