A family of eukaryotic transcription factors that recognize and bind to a highly-conserved cis-regulatory sequence (X-box) within the promoter region of MHC CLASS II GENES. They contain a conserved winged-helix DNA binding domain and function as homo or heterodimers. (mesh:D000071701)
| Synonym | Reference | Specificity |
| regulatory family X | Exact | |
| RFX | Exact | |
| RFX family | Exact | |
| RF-X | Exact | |
| RFX proteins | Exact |
| Identifier | Name | Relation |
| HGNC:9984 | RFX3 | isa |
| HGNC:9985 | RFX4 | isa |
| HGNC:9986 | RFX5 | isa |
| HGNC:9982 | RFX1 | isa |
| HGNC:9983 | RFX2 | isa |
| HGNC:25777 | RFX7 | isa |
| HGNC:21478 | RFX6 | isa |
| HGNC:37253 | RFX8 | isa |