ROR

A family of cell surface receptors that were originally identified by their structural homology to neurotropic TYROSINE KINASES and referred to as orphan receptors because the associated ligand and signaling pathways were unknown. Evidence for the functionality of these proteins has been established by experiments showing that disruption of the orphan receptor genes results in developmental defects. (mesh:D057050)

Cross-references

• BEL:ROR Family
• MESH:D057050 - Receptor Tyrosine Kinase-like Orphan Receptors
• NXP:FA:03130
• SFAM:F0209
• IP:IPR016247
• MEDSCAN:urn:agi-aopfc:0000286

Synonyms

Synonym	Reference	Specificity
RORs		Exact
receptor tyrosine kinase-like orphan receptor		Exact
receptor tyrosine kinase-like orphan receptors		Exact
ROR		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:10257	ROR2	isa
HGNC:10256	ROR1	isa

Outgoing Relations

None available.