A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES. (mesh:D019837)
Identifier | Name | Relation |
HGNC:10485 | RYR3 | isa |
HGNC:10483 | RYR1 | isa |
HGNC:10484 | RYR2 | isa |
Relation | Identifier | Name |
isa | FPLX:Ligand_gated_ion_channels | Ligand_gated_ion_channels |
isa | FPLX:Calcium_channels | Calcium_channels |