A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES. (mesh:D019837)



None available.

Incoming Relations

Identifier Name Relation
HGNC:10485 RYR3 isa
HGNC:10483 RYR1 isa
HGNC:10484 RYR2 isa

Outgoing Relations

Relation Identifier Name
isa FPLX:Calcium_channels Calcium_channels
isa FPLX:Ligand_gated_ion_channels Ligand_gated_ion_channels