SRC

A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma virus ONCOGENE PROTEIN PP60(V-SRC). They interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways. Oncogenic forms of src-family kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes. (mesh:D019061)

Cross-references

• MEDSCAN:urn:agi-aopfc:0000509
• NXP:FA:03131
• MESH:D019061 - src-Family Kinases
• SIGNOR:SIGNOR-PF32
• SFAM:F0223
• BEL:SRC Family

Synonyms

Synonym	Reference	Specificity
Src-kinases		Exact
SRC-family kinases		Exact
src kinases		Exact
SFK		Exact
Src family kinase		Exact
Src family		Exact
SFKs		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:3697	FGR	isa
HGNC:12841	YES1	isa
HGNC:11283	SRC	isa
HGNC:4037	FYN	isa

Outgoing Relations

None available.