A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many patients with acute MYELOID LEUKEMIA. (mesh:D050799)
Synonym | Reference | Specificity |
Stat5 | Exact | |
STAT5 | Exact |
Identifier | Name | Relation |
HGNC:11366 | STAT5A | isa |
HGNC:11367 | STAT5B | isa |
Relation | Identifier | Name |
isa | FPLX:STAT | STAT |