TCR

Molecules on the surface of T-lymphocytes that recognize and combine with antigens. The receptors are non-covalently associated with a complex of several polypeptides collectively called CD3 antigens (CD3 COMPLEX). Recognition of foreign antigen and the major histocompatibility complex is accomplished by a single heterodimeric antigen-receptor structure, composed of either alpha-beta (RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA) or gamma-delta (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA) chains. (mesh:D011948)

Cross-references

• MESH:D011948 - Receptors, Antigen, T-Cell
• NCIT:C17065

Synonyms

Synonym	Reference	Specificity
TcR		Exact
TCR		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:12252	TRD	partof
HGNC:12271	TRG	partof
HGNC:12155	TRB	partof
HGNC:12027	TRA	partof

Outgoing Relations

None available.