A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS. (mesh:D051193)
Synonym | Reference | Specificity |
TLR | Exact |
Identifier | Name | Relation |
HGNC:16711 | TLR6 | isa |
HGNC:11851 | TLR5 | isa |
HGNC:11847 | TLR1 | isa |
HGNC:15631 | TLR7 | isa |
HGNC:15633 | TLR9 | isa |
HGNC:15632 | TLR8 | isa |
HGNC:15634 | TLR10 | isa |
HGNC:11849 | TLR3 | isa |
HGNC:11848 | TLR2 | isa |
HGNC:11850 | TLR4 | isa |