A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS. (mesh:D051193)



Synonym Reference Specificity
TLR Exact

Incoming Relations

Identifier Name Relation
HGNC:15633 TLR9 isa
HGNC:11849 TLR3 isa
HGNC:11847 TLR1 isa
HGNC:15631 TLR7 isa
HGNC:11848 TLR2 isa
HGNC:15634 TLR10 isa
HGNC:16711 TLR6 isa
HGNC:11851 TLR5 isa
HGNC:11850 TLR4 isa
HGNC:15632 TLR8 isa

Outgoing Relations

None available.