This small family of 2 members putatively forms cation-selective ion channels. They are predicted to contain two KV-style six-transmembrane domains, suggesting they form a dimer in the membrane. These channels are closely related to CatSper channels and, more distantly, to TRP channels. (hgnc.genefamily:247)
| Identifier | Name | Relation |
| HGNC:18182 | TPCN1 | isa |
| HGNC:20820 | TPCN2 | isa |
| Relation | Identifier | Name |
| isa | FPLX:Calcium_channels | Calcium_channels |
| isa | FPLX:Voltage_gated_ion_channels | Voltage_gated_ion_channels |