VEGFR

A family of closely related RECEPTOR PROTEIN-TYROSINE KINASES that bind vascular endothelial growth factors. They share a cluster of seven extracellular IG-LIKE DOMAINS which are important for ligand binding. They are highly expressed in vascular endothelial cells and are critical for the physiological and pathological growth, development and maintenance of blood and lymphatic vessels. (mesh:D040262)

Cross-references

• GO:GO:0005172 - vascular endothelial growth factor receptor binding
• SFAM:F0246
• MESH:D040262 - Receptors, Vascular Endothelial Growth Factor
• NCIT:C17293
• BEL:VEGFR Family

Synonyms

Synonym	Reference	Specificity
VEGF receptors		Exact
VEGFR		Exact
VEGFRs		Exact
VEGF receptor		Exact

Incoming Relations

Identifier	Name	Relation
HGNC:6307	KDR	isa
HGNC:3767	FLT4	isa
HGNC:3763	FLT1	isa

Outgoing Relations

None available.