Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN. (mesh:D051153)



Synonym Reference Specificity
WNT Exact
Wnt Exact

Incoming Relations

Identifier Name Relation
HGNC:12776 WNT11 isa
HGNC:12778 WNT9A isa
HGNC:12781 WNT2B isa
FPLX:Wnt5 Wnt5 isa
HGNC:12786 WNT7A isa
HGNC:12787 WNT7B isa
HGNC:13829 WNT10A isa
HGNC:12779 WNT9B isa
HGNC:12788 WNT8A isa
HGNC:12775 WNT10B isa
HGNC:16267 WNT16 isa
HGNC:12785 WNT6 isa
HGNC:12780 WNT2 isa
HGNC:12783 WNT4 isa
HGNC:12789 WNT8B isa
HGNC:12782 WNT3 isa
HGNC:12774 WNT1 isa
HGNC:15983 WNT3A isa

Outgoing Relations

None available.