JNK

A subgroup of mitogen-activated protein kinases that activate TRANSCRIPTION FACTOR AP-1 via the phosphorylation of C-JUN PROTEINS. They are components of intracellular signaling pathways that regulate CELL PROLIFERATION; APOPTOSIS; and CELL DIFFERENTIATION. (mesh:D048031)

Cross-references

Synonyms

Synonym Reference Specificity
JNK Exact
JNK1/2 Exact
JNK MAPK Exact
SAPK Exact
c-Jun NH2-terminal kinase Exact
c-Jun N-terminal kinase Exact
c-JNK Exact
JNKs Exact

Incoming Relations

Identifier Name Relation
HGNC:6881 MAPK8 isa
HGNC:6872 MAPK10 isa
HGNC:6886 MAPK9 isa

Outgoing Relations

Relation Identifier Name
isa FPLX:MAPK MAPK