An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b ANTIGEN and the beta subunit the CD18 ANTIGEN. The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions. (mesh:D016177)



Synonym Reference Specificity
MAC-1 Exact

Incoming Relations

Identifier Name Relation
HGNC:6155 ITGB2 partof
HGNC:6149 ITGAM partof

Outgoing Relations

Relation Identifier Name
isa FPLX:Integrins Integrins