P90RSK

A family of ribosomal protein S6 kinases that are structurally distinguished from RIBOSOMAL PROTEIN S6 KINASES, 70-KDA by their apparent molecular size and the fact they contain two functional kinase domains. Although considered RIBOSOMAL PROTEIN S6 KINASES, members of this family are activated via the MAP KINASE SIGNALING SYSTEM and have been shown to act on a diverse array of substrates that are involved in cellular regulation such as RIBOSOMAL PROTEIN S6 and CAMP RESPONSE ELEMENT-BINDING PROTEIN. (mesh:D038744)

Cross-references

Synonyms

Synonym Reference Specificity
RPS6KA Exact
p90RSK Exact

Incoming Relations

Identifier Name Relation
HGNC:10434 RPS6KA5 isa
HGNC:10433 RPS6KA4 isa
HGNC:10430 RPS6KA1 isa
HGNC:10435 RPS6KA6 isa
HGNC:10432 RPS6KA3 isa
HGNC:10431 RPS6KA2 isa

Outgoing Relations

Relation Identifier Name
isa FPLX:RSK RSK