PDE4

A cyclic nucleotide phosphodiesterase subfamily that is found predominantly in inflammatory cells and may play a role in the regulation of CELL-MEDIATED IMMUNITY. The enzyme family includes over twenty different variants that occur due to multiple ALTERNATIVE SPLICING of the mRNA of at least four different genes. (mesh:D054703)

Cross-references

Synonyms

Synonym Reference Specificity
PDE4 family Exact
PDE4 Exact
type 4 cyclic nucleotide phosphodiesterase Exact
PDE4 isoforms Exact
phosphodiesterase-4 Exact
Phosphodiesterase 4 Exact
phosphodiesterase 4 Exact
Phosphodiesterase-4 Exact

Incoming Relations

Identifier Name Relation
HGNC:8782 PDE4C isa
HGNC:8781 PDE4B isa
HGNC:8783 PDE4D isa
HGNC:8780 PDE4A isa

Outgoing Relations

Relation Identifier Name
isa FPLX:PDE PDE