PDE6

A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC GMP. It is found predominantly in the outer segment PHOTORECEPTOR CELLS of the RETINA. It is comprised of two catalytic subunits, referred to as alpha and beta, that form a dimer. In addition two regulatory subunits, referred to as gamma and delta, modulate the activity and localization of the enzyme. (mesh:D054707)

Cross-references

Synonyms

Synonym Reference Specificity
PDE6 family Exact
Phosphodiesterase 6 Exact
phosphodiesterase-6 Exact
PDE6 Exact
Phosphodiesterase-6 Exact
phosphodiesterase 6 Exact

Incoming Relations

Identifier Name Relation
HGNC:8787 PDE6C isa
HGNC:8785 PDE6A isa
HGNC:8786 PDE6B isa

Outgoing Relations

Relation Identifier Name
isa FPLX:PDE PDE