STAT5

A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many patients with acute MYELOID LEUKEMIA. (mesh:D050799)

Cross-references

Synonyms

Synonym Reference Specificity
STAT5 Exact
Stat5 Exact

Incoming Relations

Identifier Name Relation
HGNC:11366 STAT5A isa
HGNC:11367 STAT5B isa

Outgoing Relations

Relation Identifier Name
isa FPLX:STAT STAT